MHN was founded in 1992 by a group of health professionals and others interested in improving the health and well-being of men, boys and families. Today, with a Board of Advisors totaling over 800 physicians and key thought leaders. It is a nonprofit incorporated in the District of Columbia. MHN has also been designated as a tax exempt organization under Section 501(c)(3) of the U.S. Internal Revenue Service code. Donations to MHN are tax deductible. MHN's Federal taxpayer identification number is 52-1855419.

MHN has received the highest rating (4 stars) from Charity Navigator.
Charity Navigator's mission states, "We help charitable givers make intelligent giving decisions by providing information on over five thousand charities and by evaluating the financial health of each of these charities. ... Charity Navigator ... does not accept any contributions from any charities we evaluate."